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Seroprevalence of malaria in inhabitants of the urban zone of Antananarivo, Madagascar / Olivier Domarle in Malaria Journal, n° 5 ([01/11/2006])
[article]
Titre : Seroprevalence of malaria in inhabitants of the urban zone of Antananarivo, Madagascar Type de document : Article/Communication Auteurs : Olivier Domarle, Auteur ; Romy Razakandrainibe, Auteur ; Emma Rakotomalala, Auteur ; Laurence Jolivet , Auteur ; Rindra Vatosoa Randremanana, Auteur ; F. Rakotomanana, Auteur ; Charles Emile Ramarokoto, Auteur ; Jean-Louis Soares, Auteur ; Frédéric Ariey, Auteur Année de publication : 2006 Note générale : bibliographie Langues : Anglais (eng) Descripteur : [Vedettes matières IGN] Applications SIG
[Termes IGN] maladie parasitaire
[Termes IGN] population urbaine
[Termes IGN] risque sanitaire
[Termes IGN] rizière
[Termes IGN] Tananarive (Madagascar)Résumé : (auteur) Background : Antananarivo, the capital of Madagascar, is located at an altitude of over 1,200 m. The environment at this altitude is not particularly favourable to malaria transmission, but malaria nonetheless remains a major public health problem. The aim of this study was to evaluate exposure to malaria in the urban population of Antananarivo, by measuring the specific seroprevalence of Plasmodium falciparum.
Methods : Serological studies specific for P. falciparum were carried out with an indirect fluorescent antibody test (IFAT). In a representative population of Antananarivo, 1,059 healthy volunteers were interviewed and serum samples were taken.
Results : The seroprevalence of IgG+IgA+IgM was 56.1% and that of IgM was 5.9%. The major risk factor associated with a positive IgG+IgA+IgM IFAT was travel outside Antananarivo, whether in the central highlands or on the coast. The abundance of rice fields in certain urban districts was not associated with a higher seroprevalence.
Conclusion : Malaria transmission levels are low in Antananarivo, but seroprevalence is high. Humans come into contact with the parasite primarily when travelling outside the city. Further studies are required to identify indigenous risk factors and intra-city variations more clearly.Numéro de notice : A2006-303 Affiliation des auteurs : COGIT+Ext (1988-2011) Thématique : GEOMATIQUE Nature : Article nature-HAL : ArtAvecCL-RevueIntern DOI : 10.1186/1475-2875-5-106 Date de publication en ligne : 10/11/2006 En ligne : https://doi.org/10.1186/1475-2875-5-106 Permalink : https://documentation.ensg.eu/index.php?lvl=notice_display&id=93947
in Malaria Journal > n° 5 [01/11/2006][article]